21c Museum Hotel St. Louis, a distinguished member of Historic Hotels of America since 2023, traces its origins back to 1926, when it breathed new life into the venerable 10-story Renaissance Revival-style YMCA building. Under the masterful guidance of the renowned interior designer Bill Rooney Studio, this 173-room boutique hotel and contemporary art museum stands as a testament to the seamless fusion of architectural heritage and curated modernity.

Nestled in the heart of downtown St. Louis, the hotel represents a thoughtful reimagination of a historic fixture, offering a unique experience that captures the essence of both the past and the present. The guestrooms and suites, designed by Bill Rooney Studio, exude a sense of tranquility and revitalization, adorned with carefully selected heirlooms and historical threads. The aesthetics are characterized by meticulously crafted classic shapes and artistic furniture designs that enhance the overall ambiance of the space.

What sets 21c Museum Hotel St. Louis apart is its distinctive design vision—a harmonious blend of architectural heritage elements and a curated modern spirit. This vision, brought to life by Bill Rooney Studio, results in spaces that not only pay homage to the original YMCA structure but also resonate with a contemplative, approachable, and slightly quirky personality. These elements seamlessly connect with the vibrant art scene of the city, creating an environment that is both inviting and culturally resonant.

Moreover, the design philosophy extends beyond the mere juxtaposition of historical and contemporary elements. Bill Rooney Studio has skillfully integrated unique hybrid contemporary art throughout the hotel, ensuring that it complements and enhances the existing architectural features. The result is a captivating experience that seamlessly weaves together the past, present, and future, making 21c Museum Hotel St. Louis a standout destination for those seeking a refined and culturally enriched stay.

Constrcution: IMEG, NuovoRE – Museum 21c Hotels

Bill Rooney Studio have been selected as a finalist for The design et al Elite Awards 2025. 

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